Ann-based model for the prediction of the bond strength between frp and concrete

In the last decades, the uses of fiber reinforced polymer (FRP) composites in the structural strengthening of reinforced concrete (RC) structures have become the state of the art, providing a valid alternative to the traditional use of steel plates. These relatively new materials present, in fact, great advantages, including high corrosion resistance in aggressive environments, low specific weight, high strength-to-mass-density ratio, magnetic and electric neutrality, low axial coefficient of thermal expansion and sustainable costs of installation. In flexural and shear strengthening of RC members, the effectiveness of the epoxy bonded FRP strongly depends on the adhesion forces exchanged with the concrete substrate. When the flexural moment is present, the FRP strengthening is activated through the stress transfer on the tension side, which is guaranteed by the contact beam region to which the adhesive is bonded to the beam itself. Hence, the determination of the maximum forces that cause debonding of the FRP-plate becomes crucial for a proper design. Over the years, many different analytical models have been provided in the scientific literature. Most of them are based on the calibration of the narrow experimental database. Now, hundreds of experimental results are available. The main goal of the current study is to present and discuss an alternative theoretical formulation for predicting the debonding force in an FRP-plate, epoxy-bonded to the concrete substrate by using an artificial neural networks (ANNs) approach. For this purpose, an extensive study of the state of the art, reporting the results of single lap shear tests, is also reported and discussed. The robustness of the proposed analytical model was validated by performing a parametric analysis and a comparison with other existing models and international design codes, as shown herein

Seismic capacity estimation of a masonry bell-tower with verticality imperfection detected by a drone-assisted survey

Masonry towers are considered an important part of cultural heritage due to their architectural and historical value. From a structural perspective these kind of buildings are considered slender elements, the same as a cantilever beam. In real cases it is not easy to model with high accuracy these heritage constructions, since the geometry and mechanical properties of the constituent materials are not adequately known. On the other hand, a deep knowledge of the structural and seismic vulnerability of the masonry towers is needed in order to preserve and retrofit, when necessary, their architectural and cultural value. In the present research an exhaustive study is presented, as it regards the assessment of the seismic vulnerability of a heritage masonry bell-tower, built in the 14th century. An innovative protocol of structural survey followed, and it is proposed herein. The geometry of the tower was easily obtained by digital photogrammetry assisted by a drone. The geometrical model was easily converted into a digitalized input, that was introduced into a finite element method (FEM)-based code. The 3D model was used for linear static, linear dynamic and nonlinear static (pushover) structural analyses. The vulnerability of the masonry tower was assessed and at least one kinematic was found to be not verified

Residual Strength and Durability of Glass fiber FRCM and CRM Systems Aged in Alkaline Environments

Fabric Reinforced Cementitious Matrix (FRCM) and Composite Reinforced Mortar (CRM) systems are used as Externally Bonded Reinforcements (EBR) in civil and historical construction. These materials are made by fibrous reinforcement, in forms of dry (FRCM) or cured (CRM) meshes embedded in a cementitious/hydraulic lime matrix. At present, this technology is considered very promising in the field of structural strengthening, retrofitting and repair existing structures. This is true especially in those cases of masonry and historical buildings, due to the specific criteria of conservation and compatibility with the substrate that need to be fulfilled. These materials, in fact, results more compatible with masonry substrate because of the inorganic matrix, instead of polymeric resin used for the well-known FRP systems (Fiber Reinforced Polymers). The recent use of these new materials in civil engineering needs appropriate and complete guidelines, that regard not only the design aspects but also the durability features. This paper presents the results of a large experimental program focused on the durability of FRCM and CRM systems and their single components, in different alkaline environments. For the whole experimental campaign, the samples have been immersed into three different alkaline solutions, for four exposure times (500, 1000, 2000 and 3000 hrs). In addition, in order to study the different accelerating effects due to temperature, three different temperatures were maintained during the ageing periods: 23°C, 40°C and 70°C. The results about the mechanical characterization of residual properties are discussed in order to highlight the influence of alkaline environments on the mechanical properties of single elements and the whole strengthening systems that were tested herein

Respiratory chain complex I, a main regulatory target of the cAMP/PKA pathway is defective in different human diseases

In mammals, complex I (NADH-ubiquinone oxidoreductase) of the mitochondrial respiratory chain has 31 supernumerary subunits in addition to the 14 conserved from prokaryotes to humans. Multiplicity of structural protein components, as well as of biogenesis factors, makes complex I a sensible pace-maker of mitochondrial respiration. The work reviewed here shows that the cAMP/PKA pathway regulates the biogenesis, assembly and catalytic activity of complex I and mitochondrial oxygen superoxide production. The structural, functional and regulatory complexity of complex I, renders it particularly vulnerable to genetic and sporadic pathological factors. Complex I dysfunction has, indeed, been found, to be associated with several human diseases. Knowledge of the pathogenetic mechanisms of these diseases can help to develop new therapeutic strategies. (C) 2011 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved

Respiratory chain complex I, a main regulatory target of the cAMP/PKA pathway is defective in different human diseases.

In mammals, complex I (NADH-ubiquinone oxidoreductase) of the mitochondrial respiratory chain has 31 supernumerary subunits in addition to the 14 conserved from prokaryotes to humans. Multiplicity of structural protein components, as well as of biogenesis factors, makes complex I a sensible pace-maker of mitochondrial respiration. The work reviewed here shows that the cAMP/PKA pathway regulates the biogenesis, assembly and catalytic activity of complex I and mitochondrial oxygen superoxide production. The structural, functional and regulatory complexity of complex I, renders it particularly vulnerable to genetic and sporadic pathological factors. Complex I dysfunction has, indeed, been found, to be associated with several human diseases. Knowledge of the pathogenetic mechanisms of these diseases can help to develop new therapeutic strategies. (C) 2011 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved

Characterization of proton irradiated 3D-DDTC pixel sensor prototypes fabricated at FBK

In this paper we discuss results relevant to 3D Double-Side Double Type Column (3D-DDTC) pixel sensors fabricated at FBK (Trento, Italy) and oriented to the ATLAS upgrade. Some assemblies of these sensors featuring different columnar electrode configurations (2, 3, or 4 columns per pixel) and coupled to the ATLAS FEI3 read-out chip were irradiated up to large proton fluences and tested in laboratory with radioactive sources. In spite of the non optimized columnar electrode overlap, sensors exhibit reasonably good charge collection properties up to an irradiation fluence of 2 x 10**15 neq/cm2, while requiring bias voltages in the order of 100 V. Sensor operation is further investigated by means of TCAD simulations which can effectively explain the basic mechanisms responsible for charge loss after irradiation.Comment: Preprint submitted to Nuclear Instruments and Methods A, 11 pages, 13 fig

Prototype ATLAS IBL Modules using the FE-I4A Front-End Readout Chip

The ATLAS Collaboration will upgrade its semiconductor pixel tracking detector with a new Insertable B-layer (IBL) between the existing pixel detector and the vacuum pipe of the Large Hadron Collider. The extreme operating conditions at this location have necessitated the development of new radiation hard pixel sensor technologies and a new front-end readout chip, called the FE-I4. Planar pixel sensors and 3D pixel sensors have been investigated to equip this new pixel layer, and prototype modules using the FE-I4A have been fabricated and characterized using 120 GeV pions at the CERN SPS and 4 GeV positrons at DESY, before and after module irradiation. Beam test results are presented, including charge collection efficiency, tracking efficiency and charge sharing.Comment: 45 pages, 30 figures, submitted to JINS